How long does a Victoza pen last once opened? Understanding the lifespan of your Victoza (liraglutide) pen is essential for safe and effective type 2 diabetes management. Once opened, a Victoza pen remains usable for exactly 1 month (30 days), regardless of how much medication remains inside. The number of doses you obtain from each pen depends on your prescribed daily dose—typically 10 to 15 days of treatment per pen for maintenance doses. Proper storage, handling, and timely disposal are crucial to maintain medication effectiveness and prevent complications. This guide explains storage requirements, expiry indicators, and practical strategies to optimise your Victoza pen usage.

How Long Does a Victoza Pen Last Once Opened?

Once you begin using a Victoza pen, it remains usable for 1 month (30 days) from the date of first use, regardless of how much medication remains inside. This timeframe applies whether the pen is stored in the refrigerator or kept at room temperature (below 30°C). After this period, you must discard the pen safely, even if it still contains liraglutide solution.

The duration a single pen lasts in terms of doses depends entirely on your prescribed daily dose. Victoza is a GLP-1 receptor agonist used once daily in type 2 diabetes. It comes in pre-filled pens containing 18 mg of liraglutide in 3 mL of solution. If you are prescribed the maintenance dose of 1.2 mg daily, a single pen will provide approximately 15 days of treatment. For those on the maximum dose of 1.8 mg daily, the same pen will last around 10 days. Patients starting treatment typically begin with 0.6 mg daily for at least one week (a starting dose for tolerability, not intended for ongoing glycaemic control), and then usually increase to a maintenance dose, meaning their first pen will typically last less than a month.

Key points to remember:

• Always write the date of first use on the pen label

• Set a reminder for 1 month after opening

• Never use a pen beyond this timeframe, even if medication remains

• Plan your prescription refills accordingly to avoid running out

• Used needles and expired pens should be disposed of in an approved sharps bin via your GP, pharmacy or local council scheme

The 1-month limit exists because once the pen seal is broken, the sterility and chemical stability of the medication can no longer be guaranteed beyond this period. Using Victoza past this date may result in reduced effectiveness or increased risk of contamination, potentially compromising your diabetes management.

Victoza Pen Storage Requirements and Shelf Life

Proper storage of your Victoza pen is essential to maintain the medication's effectiveness and safety. Before first use, unopened Victoza pens must be stored in a refrigerator at temperatures between 2°C and 8°C. Keep the pen in its original packaging to protect it from light. Under these conditions, unopened pens remain stable until the expiry date printed on the label and carton. Never freeze Victoza, and if a pen has been frozen, it must be discarded immediately, as freezing permanently damages the liraglutide molecule.

After opening, you have more flexibility with storage. The in-use pen may be kept either in the refrigerator (2°C to 8°C) or at room temperature (not exceeding 30°C) for up to 1 month (30 days). Many patients find room temperature storage more comfortable, as cold injections can be slightly more uncomfortable. However, the pen must always be kept below 30°C and away from direct heat sources such as radiators, windowsills in direct sunlight, or car glove compartments.

Important storage guidelines:

• Always replace the pen cap after each use to protect from light

• Never store the pen with a needle attached, as this can cause leakage or air bubbles

• Keep away from the freezer compartment in your refrigerator

• Do not store in excessively hot environments (above 30°C)

• Transport carefully when travelling, using a cool bag if necessary

• Keep out of the sight and reach of children

If you are unsure whether your pen has been stored correctly—for example, if it may have been exposed to extreme temperatures—contact your pharmacist for advice. Proper storage is crucial for maintaining the quality and safety of injectable diabetes medications, as outlined in the Victoza Patient Information Leaflet.

Signs Your Victoza Pen Has Expired or Gone Bad

Recognising when your Victoza pen is no longer safe to use is crucial for effective diabetes management and preventing potential adverse effects. The most straightforward indicator is the date: if 1 month (30 days) has passed since you first used the pen, or if the expiry date printed on the label has passed (for unopened pens), the medication must be discarded regardless of its appearance.

Beyond the calendar, you should inspect the solution before each injection. Victoza should always appear clear and colourless, similar to water. If you notice any of the following changes, do not use the pen:

• Cloudiness or haziness in the solution

• Discolouration (any tint of yellow, brown, or other colours)

• Visible particles, crystals, or floating matter

• Unusual thickness or texture changes

Additionally, check the pen mechanism itself. If the dose counter is not advancing properly, if the pen feels damaged, or if you notice any cracks in the cartridge, discontinue use immediately. A pen that has been dropped from a significant height should be inspected carefully, and if there is any doubt about its integrity, it should be replaced.

Physical damage indicators include:

• Cracks in the glass cartridge

• Bent or damaged needle attachment point

• Malfunctioning dose selector or injection button

• Leakage of solution from anywhere other than the needle tip during injection

If you have used a pen that you later suspect was compromised, monitor your blood glucose levels more frequently and contact your GP or diabetes specialist nurse if you notice unexpectedly high readings. Never attempt to use a pen that shows any signs of deterioration, as this could result in receiving an incorrect dose or introducing contamination. Your pharmacist can advise you, arrange dispensing with a valid prescription, and handle suspected defective product returns to the manufacturer. If you experience any side effects, report them via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk or the Yellow Card app).

How to Maximise the Lifespan of Your Victoza Pen

Whilst the 1-month in-use period cannot be extended, you can ensure your Victoza pen remains effective throughout this timeframe by following best practices for handling and storage. Consistent storage conditions are important—during use, pens may be kept in a refrigerator or at room temperature (≤30°C). Avoid extremes of temperature that fall outside the recommended range.

Handling techniques that preserve pen integrity:

• Always wash and dry your hands before handling the pen

• Attach a new needle only when ready to inject, and remove it immediately afterwards

• Never share your pen with others, even if the needle is changed

• Always replace the pen cap after use to protect from light

• Keep the pen away from direct heat and sunlight

Practical organisation strategies can help you track your pen's usability. Write the first-use date prominently on the pen label using permanent marker. Some patients find it helpful to also note the discard date (1 month later). Setting a smartphone reminder or marking your calendar ensures you do not inadvertently use an expired pen. When travelling, use an insulated medication travel case designed for injectable medications, particularly during summer months or when visiting warmer climates.

Maintain a routine for checking your medication supply. Order repeat prescriptions with sufficient time to receive new pens before your current one expires. Allow a few working days for repeat prescriptions and possible pharmacy supply delays. Having a small buffer supply prevents treatment interruptions while avoiding excessive stockpiling.

If you notice you are consistently discarding pens with significant medication remaining, discuss this with your diabetes healthcare team. They may be able to adjust your prescription to minimise waste, or confirm whether your dosing schedule is optimal.

Remember to dispose of used needles and expired pens safely in an approved sharps bin, which can be obtained from your GP surgery, pharmacy, or local council. Never dispose of needles or pens in household waste. Following the storage and handling instructions in the Victoza Patient Information Leaflet will help ensure your medication remains safe and effective throughout its in-use period.

Frequently Asked Questions