GLP-1 Brands
14
 min read

Retatrutide and Type 1 Diabetes: Evidence, Risks, and UK Guidance

Written by
Bolt Pharmacy
Published on
17/4/2026

Retatrutide and type 1 diabetes is an emerging area of scientific interest, though the evidence base remains at a very early stage. Retatrutide is an investigational triple receptor agonist developed by Eli Lilly, targeting GLP-1, GIP, and glucagon receptors simultaneously. Whilst Phase 2 trials have demonstrated significant metabolic effects in adults with obesity and type 2 diabetes, no published randomised controlled trials have included people with type 1 diabetes. This article outlines what is currently known, the potential risks, the UK regulatory position, and how to have informed conversations with your diabetes care team.

Summary: Retatrutide has not been studied in type 1 diabetes clinical trials and is

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