Supplements
12
 min read

How Much Fish Oil Per Day: UK Dosage Guidelines

Written by
Bolt Pharmacy
Published on
28/1/2026

Fish oil supplements are widely used in the UK to boost omega-3 fatty acid intake, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Understanding how much fish oil per day is appropriate depends on your dietary habits, health status, and individual needs. The NHS recommends obtaining omega-3s primarily through eating at least two portions of fish weekly, including one portion of oily fish. For those who choose supplementation, typical doses range from 250mg to 1,000mg of combined EPA and DHA daily, though requirements vary. This article explores evidence-based guidance on fish oil dosing, safety considerations, and when to seek medical advice.

Summary: Most UK adults require approximately 450mg of combined EPA and DHA daily, typically achievable through eating oily fish twice weekly or taking standard fish oil supplements.

  • Fish oil supplements contain omega-3 fatty acids (EPA and DHA) that support cardiovascular health, reduce inflammation, and aid foetal development.
  • The Scientific Advisory Committee on Nutrition recommends 450mg combined EPA/DHA daily for adults, achievable through two portions of fish weekly.
  • Standard over-the-counter supplements contain 250–1,000mg EPA/DHA per capsule; the European Food Safety Authority considers up to 5g daily safe for adults.
  • High doses may increase bleeding risk, particularly when combined with anticoagulants such as warfarin, requiring closer INR monitoring.
  • Pregnant women should avoid fish liver oils due to high vitamin A content and limit oily fish to two portions weekly.
  • Consult your GP before supplementation if taking anticoagulants, planning surgery, or considering doses exceeding 3g EPA/DHA daily.

What Is Fish Oil and Why Do People Take It?

Fish oil is a dietary supplement derived from the tissues of oily fish such as mackerel, salmon, sardines, and anchovies. It is rich in omega-3 polyunsaturated fatty acids, primarily eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These long-chain omega-3 fatty acids are produced in limited amounts by the human body from alpha-linolenic acid (ALA) and are often obtained through diet or supplementation.

Omega-3 fatty acids play crucial roles in numerous physiological processes. They are integral components of cell membranes throughout the body, particularly in the brain and retina, where DHA is highly concentrated. EPA and DHA possess anti-inflammatory properties and are involved in the regulation of blood clotting, arterial function, and immune responses. Research suggests that adequate omega-3 intake may support cardiovascular health and visual development.

People take fish oil supplements for various reasons, including:

  • Cardiovascular health – to help maintain healthy triglyceride levels

  • Joint health – for their anti-inflammatory properties in conditions such as rheumatoid arthritis, though benefits may be modest

  • Pregnancy and infant development – DHA contributes to foetal brain and eye development

  • Dietary insufficiency – when regular consumption of oily fish is limited

The NHS recommends eating at least two portions of fish per week, including one portion of oily fish, to obtain omega-3 fatty acids through diet. Whilst fish oil supplements are widely available over the counter in the UK, it is important to understand appropriate dosing, as excessive intake may carry risks. The benefits of fish oil supplementation are most evident when used appropriately and as part of a balanced diet, rather than as a replacement for healthy eating patterns.

In the UK, there is no single universal recommendation for fish oil supplementation that applies to everyone, as requirements vary based on individual health status and dietary intake. The NHS advises that most people can obtain sufficient omega-3 fatty acids by consuming at least two portions of fish per week, one of which should be oily fish (such as salmon, mackerel, or sardines). A portion is approximately 140g when cooked.

For those who choose to take fish oil supplements, typical over-the-counter products in the UK contain between 250mg and 1,000mg of combined EPA and DHA per capsule. Many manufacturers recommend one to three capsules daily, though this varies considerably between brands. The European Food Safety Authority (EFSA) has established that supplemental intakes of combined EPA and DHA of up to 5g per day are generally safe for the adult population, though most people require far less than this amount.

The Scientific Advisory Committee on Nutrition (SACN) in the UK recommends that adults consume approximately 450mg of combined EPA and DHA per day for general health, which can typically be achieved through regular fish consumption.

For specific therapeutic purposes, higher doses may be prescribed by healthcare professionals:

  • Elevated triglycerides: Prescription omega-3 preparations may be used at doses of 2-4g daily

It is important to note that NICE guidance (CG172) does not recommend omega-3 fatty acid supplements for the prevention of further heart attacks in people who have had a myocardial infarction. However, NICE (TA805) does support the use of icosapent ethyl (a purified EPA preparation) in specific high-risk patients with elevated triglycerides who are already taking statins.

Always check the EPA and DHA content on supplement labels, as total fish oil content does not reflect the actual omega-3 dose. Prescription-strength omega-3 preparations differ from standard supplements in their purity, concentration, and licensed indications.

How Much Omega-3 Do You Actually Need?

The amount of omega-3 fatty acids you require depends on whether you are seeking general health maintenance or addressing a specific health concern. The Scientific Advisory Committee on Nutrition (SACN) in the UK recommends that adults consume approximately 450mg of combined EPA and DHA per day for cardiovascular health. This recommendation is based on evidence linking omega-3 intake with reduced risk of cardiovascular disease.

For pregnant and breastfeeding women, adequate omega-3 intake is important for foetal and infant neurodevelopment. The NHS provides specific guidance on fish consumption during pregnancy rather than recommending a specific DHA intake in milligrams. Pregnant women should:

  • Eat no more than 2 portions of oily fish per week

  • Limit tuna to no more than 2 tuna steaks or 4 medium-sized cans per week (due to mercury content)

  • Avoid shark, swordfish, and marlin completely

  • Avoid fish liver oil supplements, which contain high levels of vitamin A

Children's requirements vary by age:

  • Infants and toddlers (up to 2 years): Omega-3 needs are met through breast milk or formula

  • Young children (2–11 years): Smaller portions of oily fish once or twice weekly

  • Adolescents: Similar recommendations to adults

For individuals with specific health conditions, therapeutic doses may differ substantially. For example, those with hypertriglyceridaemia may be prescribed omega-3 acid ethyl esters or icosapent ethyl under medical supervision. People with inflammatory conditions such as rheumatoid arthritis sometimes use higher doses, though evidence for benefit is modest and inconsistent.

It is important to recognise that these are omega-3 (EPA/DHA) amounts, not total fish oil amounts. A 1,000mg fish oil capsule might contain only 300mg of combined EPA and DHA, so always check the supplement facts panel to determine actual omega-3 content.

Factors That Affect Your Fish Oil Requirements

Several individual factors influence how much fish oil or omega-3 supplementation you might need. Understanding these variables can help you make informed decisions about supplementation in consultation with healthcare professionals.

Dietary intake of oily fish is the primary determinant. If you regularly consume oily fish two or more times weekly, you may already be meeting your omega-3 requirements without supplementation. Conversely, vegetarians, vegans, or those who dislike fish may have lower omega-3 status and could benefit from supplementation, potentially using algae-based omega-3 products as an alternative.

Age and life stage significantly affect requirements. During pregnancy and lactation, DHA is needed for foetal brain development, though specific NHS guidance focuses on fish consumption patterns rather than supplement doses. Children require omega-3 for growth and neurodevelopment, though in smaller absolute amounts than adults.

Existing health conditions can alter requirements:

  • Hypertriglyceridaemia: Prescription-strength omega-3 preparations may be indicated

  • Inflammatory conditions: Conditions such as rheumatoid arthritis may benefit from omega-3s, though effects are modest

  • Cardiovascular risk: NICE recommends icosapent ethyl only for specific high-risk patients already on statins

Medication use is another consideration. Anticoagulants such as warfarin may interact with fish oil, potentially affecting INR (International Normalised Ratio). If you take warfarin and fish oil supplements, your healthcare provider may need to monitor your INR more closely. Individuals taking blood pressure medications should also exercise caution, as omega-3s can have modest blood pressure-lowering effects.

Body weight may influence optimal dosing, though standard recommendations do not typically adjust for this factor. Finally, genetic variations in fatty acid metabolism can affect how efficiently individuals convert and utilise omega-3s, though genetic testing for this purpose is not routine in clinical practice.

Safety Considerations and Maximum Daily Limits

Whilst fish oil supplements are generally well-tolerated, it is important to be aware of potential adverse effects and safe upper limits. The European Food Safety Authority (EFSA) has concluded that supplemental intakes of combined EPA and DHA up to 5g per day do not raise safety concerns for the general adult population. However, the Medicines and Healthcare products Regulatory Agency (MHRA) advises caution with high doses, particularly in certain populations.

Common adverse effects of fish oil supplementation are typically mild and dose-dependent:

  • Gastrointestinal symptoms: Fishy aftertaste, belching, nausea, loose stools, or indigestion

  • Fishy body odour: Occasionally reported with higher doses

  • Mild blood thinning: May increase bleeding time, particularly relevant for those on anticoagulants

To minimise gastrointestinal side effects, take fish oil with meals, choose enteric-coated capsules, or refrigerate supplements. Starting with a lower dose and gradually increasing can also improve tolerance.

Specific safety concerns include:

  • Bleeding risk: High doses may affect bleeding tendency, particularly in combination with anticoagulants (warfarin, apixaban) or antiplatelet agents (aspirin, clopidogrel). If you take warfarin, your doctor may monitor your INR more frequently

  • Vitamin A and D toxicity: Fish liver oils (such as cod liver oil) contain these fat-soluble vitamins; excessive intake can lead to toxicity

  • Contaminants: Poor-quality supplements may contain environmental pollutants such as PCBs or dioxins, though reputable brands test for these

Pregnant women should not exceed recommended doses without medical advice, and should avoid fish liver oils due to high vitamin A content, which can be harmful during pregnancy. Quality matters: choose supplements that have been tested for purity and carry certification from reputable third-party organisations.

If you experience any suspected side effects from fish oil supplements, you can report them through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk).

When to Speak to Your GP About Fish Oil Supplements

Whilst fish oil supplements are available without prescription, there are several circumstances in which you should consult your GP before starting or continuing supplementation.

You should speak to your GP before taking fish oil if you:

  • Are taking anticoagulant or antiplatelet medications (warfarin, apixaban, rivaroxaban, aspirin, clopidogrel), as fish oil may enhance their effects and increase bleeding risk

  • Have a bleeding disorder or are scheduled for surgery (inform your surgeon and anaesthetist about all supplements you take)

  • Are pregnant or breastfeeding and considering doses above standard recommendations

  • Have diabetes, as high doses may affect blood glucose control in some individuals

  • Have a seafood allergy, though fish oil allergy is uncommon

  • Are considering giving supplements to children, as appropriate dosing differs from adults

  • Take blood pressure medications, as omega-3s may have additive effects

Seek medical advice if you are considering fish oil for:

  • Specific medical conditions such as hypertriglyceridaemia, where prescription-strength preparations may be more appropriate

  • Doses exceeding 3g of combined EPA/DHA daily, which should only be taken under medical supervision

  • Mental health conditions, where omega-3s are sometimes used as an adjunct to conventional treatment, though evidence is mixed and NICE does not routinely recommend them

Contact your GP if you experience:

  • Unusual bruising or bleeding whilst taking fish oil supplements

  • Severe gastrointestinal symptoms that persist despite adjusting timing or dose

  • Allergic reactions such as rash, swelling, or difficulty breathing

Your GP can assess whether fish oil supplementation is appropriate for your individual circumstances, recommend suitable doses, and monitor for potential interactions with your medications. In some cases, they may prescribe licensed omega-3 preparations that differ from over-the-counter supplements in their formulation and evidence base. Remember that supplements should complement, not replace, a balanced diet rich in whole foods, including oily fish where appropriate.

If you experience any suspected side effects from fish oil supplements, report them through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk).

Frequently Asked Questions

Can I take fish oil if I'm on warfarin?

You should consult your GP before taking fish oil with warfarin, as omega-3 supplements may enhance anticoagulant effects and increase bleeding risk. Your doctor may need to monitor your INR more frequently if you take both.

Is it safe to take fish oil during pregnancy?

Standard fish oil supplements are generally safe during pregnancy, but avoid fish liver oils due to high vitamin A content. The NHS recommends limiting oily fish to two portions weekly and avoiding certain fish species due to mercury content.

What's the difference between total fish oil and EPA/DHA content?

Total fish oil content includes all fats in the capsule, whilst EPA and DHA are the active omega-3 fatty acids. A 1,000mg fish oil capsule may contain only 300mg of combined EPA/DHA, so always check the supplement facts panel for actual omega-3 content.


Disclaimer & Editorial Standards

The health-related content published on this site is based on credible scientific sources and is periodically reviewed to ensure accuracy and relevance. Although we aim to reflect the most current medical knowledge, the material is meant for general education and awareness only.

The information on this site is not a substitute for professional medical advice. For any health concerns, please speak with a qualified medical professional. By using this information, you acknowledge responsibility for any decisions made and understand we are not liable for any consequences that may result.

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